Concepedia

Optimization of feed rate profile for the monoclonal antibody production

J.-H. Lee, Hyungsik Lim, Yomoon Yoo, Y. H. Park

Bioprocess Engineering · 1999 · 18 citations · 6 references

DOI

Concepts

References

6

Computational algorithms for optimal feed rates for a class of fed‐batch fermentation: Numerical results for penicillin and cell mass production

Hyungsik Lim, Y. J. Tayeb, Jayant M. Modak et al. · Biotechnology and Bioengineering · 1986 · 155 citations

, , +17

A structured kinetic modeling framework for the dynamics of hybridoma growth and monoclonal antibody production in continuous suspension cultures

Brian C. Batt, Dhinakar S. Kompala · Biotechnology and Bioengineering · 1989 · 128 citations

, , +14

Optimization of fed-batch culture of hybridoma cells using dynamic programming: single and multi feed cases

Michèle Tremblay, C. Chavarie, Jean Archambault · Bioprocess and Biosystems Engineering · 1992 · 103 citations

, , +13

The enhancement of specific antibody production rate in glucose- and glutamine-controlled fed-batch culture

Takeshi Ōmasa, Masaru Ishimoto, Kenichi Higashiyama et al. · Cytotechnology · 1992 · 58 citations

, , +7

Simulation of animal cell metabolism

J. P. Barford, Peter J. Phillips, Colin Harbour · Cytotechnology · 1992 · 32 citations

, , +12