Concepedia

D-amino acid oxidase gene therapy sensitizes glioma cells to the antiglycolytic effect of 3-bromopyruvate

Shahin Sayed, Rabab M Abou El-Magd, Yuji Shishido, Seong Pil Chung, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami, Kiyoshi Fukui

Cancer Gene Therapy · 2011 · 45 citations · 37 references

DOI

Concepts

References

37

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

Sergey Korshunov, Vladimir P. Skulachev, Anatoly A. Starkov · FEBS Letters · 1997 · 1.7K citations · Full text

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Spheroid-based drug screen: considerations and practical approach

Juergen Friedrich, Claudia Seidel, Reinhard Ebner et al. · Nature Protocols · 2009 · 1.7K citations

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Metabolic Modulation of Glioblastoma with Dichloroacetate

Evangelos D. Michelakis, Gopinath Sutendra, Peter Dromparis et al. · Science Translational Medicine · 2010 · 715 citations

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Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

Paul A. Hyslop, Daniel B. Hinshaw, W A Halsey et al. · Journal of Biological Chemistry · 1988 · 624 citations · Full text

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