Histone H1 Depletion in Mammals Alters Global Chromatin Structure but Causes Specific Changes in Gene Regulation

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Andrew P. Feinberg, Bert Vogelstein · Analytical Biochemistry · 1983 · 25.2K citations

Nucleic Acid Chemistry, High Specific Activity, Natural Sciences +6

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 3.9K citations

Developmental Biology, Embryonic Lethality, Epigenetic Change +8

Role for DNA methylation in genomic imprinting

Rudolf Jaenisch · Nature · 1993 · 1.9K citations

Chromatin, Epigenetic Change, Genetics +5

High sensitivity mapping of methylated cytosines

J.CIark Susan, Cheryl Paul, Marianne Frommer · Nucleic Acids Research · 1994 · 1.9K citations · Full text

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

Adam C. Bell, Gary Felsenfeld · Nature · 2000 · 1.7K citations

Chromatin, Developmental Biology, Igf2 Gene +9