Concepedia

The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex

Emily Heikamp, Chirag H. Patel, Sam Collins, Adam T. Waickman, Min Hee Oh, Im‐Hong Sun, Peter B. Illei, Archna Sharma, Anikó Náray‐Fejes‐Tóth, Géza Fejes‐Tóth,

Nature Immunology · 2014 · 195 citations · 36 references

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References

36

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.2K citations

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Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism

Chunming Liu, Yiming Li, Mikhail A. Semenov et al. · Cell · 2002 · 2.1K citations · Full text

, , +12

Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

David A. Guertin, Deanna M. Stevens, Carson C. Thoreen et al. · Developmental Cell · 2006 · 1.4K citations · Full text

, , +10

SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity

Estela Jacinto, Valeria Facchinetti, Dou Liu et al. · Cell · 2006 · 1.4K citations · Full text

, , +13

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

Markus Kleinewietfeld, Arndt Manzel, Jens Titze et al. · Nature · 2013 · 1.4K citations · Full text

, , +16