Tumor-conditioned medium increases macromolecular permeability of endothelial cell monolayer

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Medicine, Oncology, Pharmacology +12

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

Donald R. Senger, Stephen J. Galli, Ann M. Dvořàk et al. · Science · 1983 · 4K citations

Medicine, Biochemistry, Oncology +13

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

Pamela J. Keck, Scott D. Hauser, Gwen G. Krivi et al. · Science · 1989 · 2.1K citations

Life Sciences, Biochemistry, Molecular Biology +13

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

Bruce R. Stevenson, Janet D. Siliciano, Mark S. Mooseker et al. · The Journal of Cell Biology · 1986 · 1.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In Vitro

Marie‐Pierre Dehouck, Stéphane Méresse, Pierre Delorme et al. · Journal of Neurochemistry · 1990 · 543 citations

Engineering, Cell Biology, Neuroscience +17