Retention of Structural and Biochemical Integrity in a Biological Mesh Supports Tissue Remodeling in a Primate Abdominal Wall Model

Abstract

The combination of a nondamaging process, successful removal of cells, and reduction of the xenogeneic alpha-Gal antigens from the porcine dermal matrix, while maintaining an intact extracellular matrix, is critical to its ability to remodel and integrate into host tissue, leading to its overall acceptance.