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Publication | Open Access

Overexpression of 17β-Hydroxysteroid Dehydrogenase Type 1 Increases the Exposure of Endometrial Cancer to 17β-Estradiol

DOIFull Paper Access

64

Citations

27

References

2012

Year

Karlijn Cornel, Roy F.P.M. Kruitwagen, Bert Delvoux, Laura Visconti, Koen Van de Vijver, Joanna M. Day, Toon Van Gorp, Rob Hermans, Gerard A.J. Dunselman, Andrea Romano
The Journal of Clinical Endocrinology & Metabolism

Abstract

Type 1 17β-HSD increases 17β-estradiol exposure in grade 1 EC, thus supporting tumor growth. This enzyme represents a potential therapeutic target.

References

YearCitations

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