Emerging infectious diseases · 2009 · 93 citations · 15 references
Life SciencesInfectious DiseasesMicrobiologyMedical MicrobiologyMolecular VirologyVirologyAntiviral Drug ResistanceAntiviral ResistanceAntiviral TherapyRespiratory Infectious DiseasesViral GeneticsViral InfectionsAntiviral Resistance PreventionDrug Resistance MonitoringInfluenza Antiviral ResistanceInfluenza Antiviral TherapyInfluenza TreatmentMolecular Epidemiology Of VirusesNeuraminidase Inhibitor ResistanceResistance-associated Mutations
Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.
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Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic
Gavin J. D. Smith, Dhanasekaran Vijaykrishna, Justin Bahl et al. · Nature · 2009 · 2.3K citations · Full text
Resistant influenza A viruses in children treated with oseltamivir: descriptive study
Maki Kiso, Keiko Mitamura, Yuko Sakai‐Tagawa et al. · The Lancet · 2004 · 795 citations