Concepedia

Quantitative PK–PD Model-Based Translational Pharmacology of a Novel Kappa Opioid Receptor Antagonist Between Rats and Humans

Cheng Chang, Wonkyung Byon, Yifeng Lu, Leslie K. Jacobsen, Lori L. Badura, Aarti Sawant‐Basak, Emily Miller, Jing Liu, Sarah Grimwood, Ellen Q. Wang,

The AAPS Journal · 2011 · 42 citations · 23 references

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References

23

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

G. Di Chiara, Assunta Impérato · Journal of Pharmacology and Experimental Therapeutics · 1988 · 922 citations

, , +17

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

Harold Boxenbaum · Journal of Pharmacokinetics and Biopharmaceutics · 1982 · 646 citations

, , +11

Evaluating Pharmacokinetic/Pharmacodynamic Models Using the Posterior Predictive Check

Yoshitaka Yano, Stuart L. Beal, Lewis B. Sheiner · Journal of Pharmacokinetics and Pharmacodynamics · 2001 · 402 citations

, , +14

Species, strain and sex differences in metabolism of hexobarbitone, amidopyrine, antipyrine and aniline

Julius Axelrod, Bernard B. Brodie · Biochemical Pharmacology · 1958 · 371 citations

, , +9

Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance.

A Rane, G. Wilkinson, David G. Shand · Journal of Pharmacology and Experimental Therapeutics · 1977 · 328 citations

, , +17