Apolipoprotein E deficiency effects on learning in mice are dependent upon the background strain

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

Andrew Plump, Jonathan D. Smith, Tony Hayek et al. · Cell · 1992 · 2.3K citations

Life Sciences, Genetics, Molecular Genetics +10

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

Sunny H. Zhang, Robert L. Reddick, Jorge A. Piedrahita et al. · Science · 1992 · 2.2K citations

Life Sciences, Cardiology, Genetics +17

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

Lindsay A. Farrer · JAMA · 1997 · 1.9K citations

Medicine, Genetics, Neurology +17

Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging

RM Sapolsky, L.C. Krey, BS McEwen · Journal of Neuroscience · 1985 · 1.1K citations · Full text

Education, Neurobiology, Neuroscience +17

Retinal degeneration in the rd mouse is caused by a defect in the β subunit of rod cGMP-phosphodiesterase

Cathy Bowes, Tiansen Li, Michael Danciger et al. · Nature · 1990 · 858 citations

Medicine, Neuroscience, Ophthalmology +17