Synthesis of the nucleopeptides H-Phe-Tyr(pGC)-NH<sub>2</sub>and H-Phe-Ser(pGC)-Ala-OH via a phosphotriester approach

E. Kuyl‐Yeheskiely, C.M. Dreef-Tromp, Annemieke Geluk, G. A. VAN DER MAREL, Jacques H. van Boom

Nucleic Acids Research · 1989 · 28 citations · 5 references

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Abstract

Use of the protecting groups di-n-butylaminomethylene,2-nitrophenylsulfenyl and the ester of 2-(hydroxymethyl)-9,10-anthraquinone, enabled us for the first time to prepare nucleopeptide fragments containing 2'-deoxyguanosine and a free carboxylic acid group.

References

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