Brian C. Froehler

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Active since

1983

Affiliations

Gilead Sciences (United States)(Current)

Gene Therapy Laboratory

Sunesis (United States)

Brian C. Froehler is an author at Gilead Sciences (United States) specializing in molecular biology, oligonucleotide chemistry, and nucleic acid biochemistry.

Publications per year

1983–2003

Publications

Antisense Gene Inhibition by Oligonucleotides Containing C-5 Propyne Pyrimidines

Richard W. Wagner, Mark D. Matteucci, Jason G. Lewis et al. · Science · 1993 · 406 citations

Life Sciences, Molecular Biology, Molecular Genetics +17

Modified deoxyoligonucleotides stable to exonuclease degradation in serum

Jeng‐Pyng Shaw, Kenneth M. Kent, Jeff Bird et al. · Nucleic Acids Research · 1991 · 369 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Synthesis of DNA via deoxynudeoside H-phosphonate Intermediates

Brian C. Froehler, Peter G. Ng, Mark D. Matteucci · Nucleic Acids Research · 1986 · 345 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Nucleoside h-phosphonates: Valuable intermediates in the synthesis of deoxyoligonucleotides

Brian C. Froehler, Mark D. Matteucci · Tetrahedron Letters · 1986 · 185 citations

Pharmacy, Biochemistry, Nucleic Acid Biochemistry +10

Oligodeoxynucleotides containing C-5 propyne analogs of 2′-deoxyuridine and 2′-deoxycytidine

Brian C. Froehler, Shalini Wadwani, Terry Terhorst et al. · Tetrahedron Letters · 1992 · 183 citations

Pharmacy, Biochemistry, Molecular Biology +12

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