Dialkylformamldines: depurination resistant N<sup>6</sup>-protecting group for deoxyadenosine

Brian C. Froehler, Mark D. Matteucci

Nucleic Acids Research · 1983 · 125 citations · 3 references

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Abstract

Sterically hindered N6-dialkylformamidine protected deoxyadenosine is more stable to acidic depurination than N6-benzoyldeoxyadenosine and is potentially a valuable protecting group in the synthesis of deoxyoligonucleotides.

References

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