Synthesis of defucogilvocarcin V isosteres via MAD-mediated conjugate addition of carbanions to naphthoquinone ketals

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

Natural Sciences, Chemistry, Catalysis +11

13. Researches on acetylenic compounds. Part I. The preparation of acetylenic ketones by oxidation of acetylenic carbinols and glycols

K. Bowden, I. M. Heilbron, E. R. H. Jones et al. · Journal of the Chemical Society (Resumed) · 1946 · 906 citations

Natural Sciences, Biochemistry, Chemistry +3

The Substitution of Aryl Iodides with Cuprous Acetylides. A Synthesis of Tolanes and Heterocyclics¹

Robert D. Stephens, C. E. Castro · The Journal of Organic Chemistry · 1963 · 623 citations

Natural Sciences, Chemistry, Analytical Chemistry +7

Synthesis of Aromatic Heterocycles via Palladium-Catalyzed Annulation of Internal Alkynes

Richard C. Larock, Mark J. Doty, Kelvin Sham · The Journal of Organic Chemistry · 1995 · 290 citations

Natural Sciences, Chemistry, Analytical Chemistry +12

Total Synthesis of the Gilvocarcins

Takamitsu Hosoya, Eiji Takashiro, Takashi Matsumoto et al. · Journal of the American Chemical Society · 1994 · 251 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7