Synthesis of chiral pharmaceutical intermediates by biocatalysis

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

M. C. Wani, Harold L. Taylor, Monroe E. Wall et al. · Journal of the American Chemical Society · 1971 · 4.1K citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Promotion of microtubule assembly in vitro by taxol

Peter B. Schiff, Jane Fant, Susan Band Horwitz · Nature · 1979 · 3.6K citations

Life Sciences, Biochemistry, Cell Biology +9

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

Miguel A. Ondetti, Bernard Rubin, David W. Cushman · Science · 1977 · 1.9K citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein, Wen‐Yang Wu, Gaik B. Kok et al. · Nature · 1993 · 1.9K citations

Pharmacy, Medicinal Chemistry, Molecular Biology +16