A concise preparation of the non-proteinogenic amino acid l-kynurenine

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Christiane A. Opitz, Ulrike Litzenburger, Felix Sahm et al. · Nature · 2011 · 1.9K citations · Full text

Medicine, Cancer Biology, Oncology +13

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

Joshua D. Mezrich, John H. Fechner, Xiaoji Zhang et al. · The Journal of Immunology · 2010 · 1.6K citations · Full text

Life Sciences, Immunology, Pharmacology +15

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

Daniel Zwilling, Shaoyi Huang, Korrapati V. Sathyasaikumar et al. · Cell · 2011 · 514 citations · Full text

Life Sciences, Neuroscience, Pharmacology +10

Kynurenine is an endothelium-derived relaxing factor produced during inflammation

Yutang Wang, Hanzhong Liu, Gavin McKenzie et al. · Nature Medicine · 2010 · 450 citations

Veterinary Medicine, Pharmacology, Physiology +12

IDO and interferon-α-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity

Marieke Wichers, Ger H. Koek, Geert Robaeys et al. · Molecular Psychiatry · 2004 · 441 citations

Nursing, Neuroscience, Psychiatry +13