Retinoic Acid–Induced Pancreatic Stellate Cell Quiescence Reduces Paracrine Wnt–β-Catenin Signaling to Slow Tumor Progression

Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

Gordon K. Smyth · Statistical Applications in Genetics and Molecular Biology · 2004 · 11.9K citations

Transcriptomics Technology, Empirical Bayes Methods, Linear Models +21

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

Siân Jones, D. Williams Parsons, Jimmy Lin et al. · Science · 2008 · 4K citations · Full text

Engineering, Genetics, Pathology +17

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

Kenneth P. Olive, Michael A. Jacobetz, Christian J. Davidson et al. · Science · 2009 · 3.1K citations · Full text

Tumor Biology, Oncology, Pancreatic Cancer +12

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

Sunil R. Hingorani, Lifu Wang, Asha S. Multani et al. · Cancer Cell · 2005 · 2.6K citations · Full text

Genome Instability, Pancreatic Cancer, Chromosomal Instability +7

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

Cédric Gaggioli, Steven Hooper, Cristina Hidalgo-Carcedo et al. · Nature Cell Biology · 2007 · 1.5K citations

Cancer Research, Oncology, Malignant Disease +10