Concepedia

The conformation of hepatitis C virus NS3 proteinase with and without NS4A: a structural basis for the activation of the enzyme by its cofactor

Robert A. Love, Hans E. Parge, John Wickersham, Zdeněk Hostomský, Noriyuki Habuka, Ellen W. Moomaw, Tsuyoshi Adachi, Steve Margosiak, Eleanor Dagostino, Zuzana Hostomska

Clinical and Diagnostic Virology · 1998 · 43 citations · 7 references

DOI

Concepts

References

7

Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide

J.L Kim, Kurt Morgenstern, Chao Lin et al. · Cell · 1996 · 728 citations · Full text

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The Crystal Structure of Hepatitis C Virus NS3 Proteinase Reveals a Trypsin-like Fold and a Structural Zinc Binding Site

Robert A. Love, Hans E. Parge, John Wickersham et al. · Cell · 1996 · 506 citations · Full text

, , +15

Activity of purified hepatitis C virus protease NS3 on peptide substrates

Christian Steinkühler, Andrea Urbani, Licia Tomei et al. · Journal of Virology · 1996 · 142 citations · Full text

, , +17

Mechanistic Role of an NS4A Peptide Cofactor with the Truncated NS3 Protease of Hepatitis C Virus:  Elucidation of the NS4A Stimulatory Effect <i>via</i> Kinetic Analysis and Inhibitor Mapping

James A. Landro, Scott A. Raybuck, Yu Ping C. Luong et al. · Biochemistry · 1997 · 106 citations

, , +17

Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease

Yoshiyuki Shimizu, Kayo Yamaji, Yasuhiko Masuho et al. · Journal of Virology · 1996 · 105 citations · Full text

, , +17