Noriyuki Habuka

Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complex

Charles R. Kissinger, Hans E. Parge, Daniel R. Knighton et al. · Nature · 1995 · 760 citations

Protein Chemistry, Crystal Structure, Engineering +9

The Crystal Structure of Hepatitis C Virus NS3 Proteinase Reveals a Trypsin-like Fold and a Structural Zinc Binding Site

Robert A. Love, Hans E. Parge, John Wickersham et al. · Cell · 1996 · 506 citations · Full text

Virus Structure, Crystal Structure, Biochemistry +8

Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein

Kathleen Aertgeerts, R.J. Skene, Jason K. Yano et al. · Journal of Biological Chemistry · 2011 · 414 citations · Full text

Crystal Structure, Molecular Biology, Cancer Biology +22

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

Hideo Ago, Tsuyoshi Adachi, Atsuhito Yoshida et al. · Structure · 1999 · 408 citations · Full text

Virus Structure, Crystal Structure, Viral Replication +10

Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-<i>d</i>]pyrimidine Scaffold

Tomoyasu Ishikawa, Masaki Seto, Hiroshi Banno et al. · Journal of Medicinal Chemistry · 2011 · 207 citations · Full text

Dual Inhibitors Bearing, Medicinal Chemistry, Dual Inhibitors +12