Disruption of Na <sup>+</sup> ,HCO <sub>3</sub> <sup>−</sup> Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca <sup>2+</sup> Sensitivity, and Hypertension Development in Mice - Concepedia

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Disruption of Na <sup>+</sup> ,HCO <sub>3</sub> <sup>−</sup> Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca <sup>2+</sup> Sensitivity, and Hypertension Development in Mice

135

Citations

35

References

2011

Year

Ebbe Boedtkjer, Jeppe Prætorius, Vladimir V. Matchkov, Edgaras Stankevıčıus, Susie Mogensen, Annette Füchtbauer, Ulf Simonsen, Ernst‐Martin Füchtbauer

Abstract

Intracellular acidification of smooth muscle and endothelial cells after knockout of NBCn1 inhibits NO-mediated and rho-kinase-dependent signaling in isolated arteries and perturbs blood pressure regulation.

References

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