Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

Masayoshi Uehata, Toshimasa Ishizaki, Hiroyuki Satoh, +8

Nature

HypertensionMuscle FunctionSignal TransductionMolecular PhysiologyCalcium Sensitization +9

Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases

Toshimasa Ishizaki, Masayoshi Uehata, Ichiro Tamechika, +4

Molecular Pharmacology

An essential part for Rho–associated kinase in the transcellular invasion of tumor cells

Kazuyuki Itoh, Kiyoko Yoshioka, Hitoshi Akedo, +3

Nature Medicine

Cancer ResearchTranscellular InvasionSignal TransductionSignaling PathwayMedicine +11

Molecular Dissection of the Rho-associated Protein Kinase (p160ROCK)-regulated Neurite Remodeling in Neuroblastoma N1E-115 Cells

Toshimasa Ishizaki, Naoki Watanabe, Masayoshi Uehata, +6

The Journal of Cell Biology

Effects of Topical Administration of Y-39983, a Selective Rho-Associated Protein Kinase Inhibitor, on Ocular Tissues in Rabbits and Monkeys

Hideki Tokushige, Masaru Inatani, Shingo Nemoto, +4

Investigative Ophthalmology & Visual Science

Effect of Wf-536, a novel ROCK inhibitor, against metastasis of B16 melanoma

Masahide Nakajima, Kazutaka Hayashi, Yasuhiro Egi, +10

Cancer Chemotherapy and Pharmacology

Tumor BiologyOncologyMedicineMelanomaPathology +5

Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions

Masahide Nakajima, Kazutaka Hayashi, Kenichi Katayama, +5

European Journal of Pharmacology

Tumor MotilityAngiogenesisMedicineAngiogenic ActionsPathology +6

The Suppression of Small GTPase Rho Signal Transduction Pathway Inhibits Angiogenesis in Vitro and in Vivo

Shigeki Uchida, Go Watanabe, Yutaka Shimada, +8

Biochemical and Biophysical Research Communications

AngiogenesisSignal TransductionCell SignalingVascular AdaptationImmunology +7

Direct in Vitro and in Vivo Evidence for Interaction between Hsp47 Protein and Collagen Triple Helix

Takashi Ono, Takahiro Miyazaki, Yoshihito Ishida, +2

Journal of Biological Chemistry

Protein AssemblyUnfolded Procollagen ChainsMolecular BiologyCytoskeletonCollagen Model Peptide +16

Small Guanosine Triphospatase RhoA and Rho-Associated Kinase as Regulators of Trophoblast Migration

Shigetatsu Shiokawa, Mitsutoshi Iwashita, Yoshihiro Akimoto, +7

The Journal of Clinical Endocrinology & Metabolism