Hypertension in mice lacking the gene for endothelial nitric oxide synthase

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.8K citations

Veterinary Medicine, Cell Biology, Physiology +10

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

L J Ignarro, Georgette M. Buga, K S Wood et al. · Proceedings of the National Academy of Sciences · 1987 · 5.1K citations · Full text

Medicine, Pharmacology, Physiology +12

Histochemical mapping of nitric oxide synthase in the rat brain

S.R. Vincent, Hiroshi Kimura · Neuroscience · 1992 · 1.9K citations

Life Sciences, Neurobiology, Neuroscience +10

Characterization of three inhibitors of endothelial nitric oxide synthase <i>in vitro</i> and <i>in vivo</i>

Daryl D. Rees, Richard Palmer, Richard Schulz et al. · British Journal of Pharmacology · 1990 · 1.9K citations · Full text

Medicine, Cardiology, Pharmacology +12

Role of endothelium-derived nitric oxide in the regulation of blood pressure.

Daryl D. Rees, Richard Palmer, Salvador Moncada · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

Medicine, Cardiology, Pharmacology +12