Concepedia

Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism) — Increased michaelis constant (km) and loss of stereoselectivity of bufuralol 1′-hydroxylation in poor metabolizers

Pierre Dayer, Rodolfo Gasser, J. Gut, Thomas Kronbach, Gerda-Marie Robertz, Michel Eichelbaum, Urs Meyer

Biochemical and Biophysical Research Communications · 1984 · 66 citations · 14 references

DOI

Concepts

References

14

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

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POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

A. Mahgoub, L. G. Dring, Jeffrey R. Idle et al. · The Lancet · 1977 · 1.2K citations

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Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

Y. Yasukochi, Bettie Sue Siler Masters · Journal of Biological Chemistry · 1976 · 1.2K citations · Full text

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Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

F. Peter Guengerich, Ghazi A. Dannan, Stephen Wright et al. · Biochemistry · 1982 · 1K citations

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A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

David A. Evans, A. Mahgoub, T.P. Sloan et al. · Journal of Medical Genetics · 1980 · 540 citations · Full text

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