Cathepsin S Is Activated During Colitis and Causes Visceral Hyperalgesia by a PAR2-Dependent Mechanism in Mice

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

Martin Steinhoff, Nathalie Vergnolle, Steven H. Young et al. · Nature Medicine · 2000 · 931 citations

Life Sciences, Neurobiology, Neuroscience +10

Cathepsin S Required for Normal MHC Class II Peptide Loading and Germinal Center Development

Guo‐Ping Shi, Jóse A. Villadangos, Glenn Dranoff et al. · Immunity · 1999 · 522 citations · Full text

Life Sciences, Biochemistry, Immunology +14

Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain

Anna K. Clark, Ping K. Yip, John Grist et al. · Proceedings of the National Academy of Sciences · 2007 · 481 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

Nathalie Vergnolle, Nigel W. Bunnett, Keith A. Sharkey et al. · Nature Medicine · 2001 · 472 citations

Life Sciences, Molecular Biology, Pharmacology +14

Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes

Galia Blum, Georges von Degenfeld, Milton Merchant et al. · Nature Chemical Biology · 2007 · 464 citations

Natural Sciences, Biochemistry, Biophysics +16