Concepedia

PTEN-Mediated Apical Segregation of Phosphoinositides Controls Epithelial Morphogenesis through Cdc42

Fernando Martín‐Belmonte, Ama Gassama, Anirban Datta, Wei Yu, Ursula Rescher, Volker Gerke, Keith E. Mostov

Cell · 2007 · 698 citations · 42 references

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42

The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate

Tomohiko Maehama, Jack E. Dixon · Journal of Biological Chemistry · 1998 · 3.1K citations · Full text

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The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

Gérard Joberty, Clark Petersen, Lin Gao et al. · Nature Cell Biology · 2000 · 918 citations

, , +13

Characterization of Rac and Cdc42 Activation in Chemoattractant-stimulated Human Neutrophils Using a Novel Assay for Active GTPases

Valérie Planat‐Benard, Benjamin P. Bohl, Gary Bokoch · Journal of Biological Chemistry · 1999 · 754 citations · Full text

, , +15

Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain

Kathryn M. Ferguson, Mark A. Lemmon, Joseph Schlessinger et al. · Cell · 1995 · 600 citations · Full text

, , +16

Endothelial tubes assemble from intracellular vacuoles in vivo

Makoto Kamei, W. Brian Saunders, Kayla J. Bayless et al. · Nature · 2006 · 515 citations

, , +14