Concepedia

SUMO‐1 modification activates the transcriptional response of p53

Manuel S. Rodríguez, Joana Desterro, Carol Midgley, David P. Lane, Ronald T. Hay

The EMBO Journal · 1999 · 634 citations · 57 references

DOI

Concepts

References

57

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

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Participation of p53 protein in the cellular response to DNA damage.

Michael B. Kastan, Onyinye Onyekwere, D Sidransky et al. · PubMed · 1991 · 3.8K citations

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Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

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DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2

Sheau-Yann Shieh, Masako Ikeda, Yoichi Taya et al. · Cell · 1997 · 2.1K citations · Full text

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