Concepedia

Receptor and ligand-based 3D-QSAR study on a series of nonsteroidal anti-inflammatory drugs

Souhila Terrachet-Bouaziz, Redouane Terrachet, Safia Taïri-Kellou

Medicinal Chemistry Research · 2012 · 15 citations · 29 references

Concepts

PharmacyMedicinal ChemistryPharmacologyDrug DesignDrug DiscoveryPharmacophore ModelingLigand BindingLigand-based DesignMolecular DockingProtein-ligand DockingReceptor ModelingReceptor-ligand InteractionsAnti-inflammatory Drug DiscoveryPharmacophore Model ConstructionReceptor-based Pharmacophore GenerationReceptor-based Pharmacophore ScreeningReceptor-ligand Structural Biology

References

29

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

Life Sciences, Biochemistry, Bioinformatics +10

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

Garrett M. Morris, David S. Goodsell, Robert S. Halliday et al. · Journal of Computational Chemistry · 1998 · 10.8K citations

Life Sciences, Bioinformatics, Molecular Biology +17

Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

Richard D. Cramer, David E. Patterson, Jeffrey D. Bunce · Journal of the American Chemical Society · 1988 · 3.9K citations

Life Sciences, Biochemistry, Pharmacology +14

Alexander Golbraikh, Alexander Tropsha · Journal of Molecular Graphics and Modelling · 2002 · 3.7K citations

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

Ravi G. Kurumbail, Anna M. Stevens, James K. Gierse et al. · Nature · 1996 · 1.9K citations

Pharmacy, Medicinal Chemistry, Pharmacology +16