Concepedia

Allergic Sensitization through the Airway Primes Th17-dependent Neutrophilia and Airway Hyperresponsiveness

Rhonda H. Wilson, Gregory S. Whitehead, Hideki Nakano, Meghan E. Free, Jay K. Kolls, Donald N. Cook

American Journal of Respiratory and Critical Care Medicine · 2009 · 398 citations · 27 references

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Abstract

Allergic sensitization through the airway primes modest Th2 responses but strong Th17 responses that promote airway neutrophilia and acute AHR. These findings support a causal role for neutrophils in severe asthma.

References

27

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