Concepedia

Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity

Cristian A. Lasagna‐Reeves, Audra L. Clos, Diana L. Castillo‐Carranza, Urmi Sengupta, Marcos J. Guerrero-Muñoz, Brent Kelly, Richard F. Wagner, Rakez Kayed

Biochemical and Biophysical Research Communications · 2012 · 86 citations · 18 references

DOI

Concepts

References

18

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

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[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

Harry LeVine · Methods in enzymology on CD-ROM/Methods in enzymology · 1999 · 1.4K citations

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Misfolded proteins partition between two distinct quality control compartments

Daniel Kaganovich, Ron R. Kopito, Judith Frydman · Nature · 2008 · 963 citations · Full text

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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

Rakez Kayed, Elizabeth Head, Floyd Sarsoza et al. · Molecular Neurodegeneration · 2007 · 782 citations · Full text

, , +17

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

Jie Xu, Joke Reumers, José R. Couceiro et al. · Nature Chemical Biology · 2011 · 538 citations

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