A scalable SCENIC workflow for single-cell gene regulatory network analysis

Bram Van de Sande, Christopher Flerin, Kristofer Davie, +12

Nature Protocols

EngineeringGeneticsGene Regulatory NetworkTrajectory AnalysisSingle Cell Sequencing +14

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

Sebastian Maurer‐Stroh, Maja Debulpaep, Nico Kuemmerer, +9

Nature Methods

Neuroimaging BiomarkersAlzheimer's DiseasePosition-specific Scoring MatricesComputational BiologySequence Determinants +8

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Yao‐Cheng Lin, Morgane Boone, Leander Meuris, +13

Nature Communications

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

Jie Xu, Joke Reumers, José R. Couceiro, +11

Nature Chemical Biology

Mutant P53Tumor BiologyOncogenic AgentMedicineCancer Biology +7

SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants

Greet De Baets, Joost Van Durme, Joke Reumers, +4

Nucleic Acids Research

Structural BioinformaticsGeneticsSingle Nucleotide VariantsMolecular BiologySnpeffect 4.0 +22

Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing

Joke Reumers, Peter De Rijk, Hui Zhao, +12

Nature Biotechnology

PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes

Lucía Conde, Juan M. Vaquerizas, Hernán Dopazo, +4

Nucleic Acids Research

Functional validation of a genetic locus in the VEGFR-1 tyrosine kinase (TK) domain as a predictive marker for bevacizumab

Bart Claes, Paul Delmar, Betül T. Yesilyurt, +9

ePrints Soton (University of Southampton)

VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials

Diether Lambrechts, Bart Claes, Paul Delmar, +11

The Lancet Oncology

Genetic VariantsTreatment OutcomeAngiogenesisNovel TherapyMedicine +7

SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs

Joke Reumers

Nucleic Acids Research

GeneticsGenetic EpidemiologyHuman PolymorphismMolecular BiologyGene Characterization +14