DNA immunization is associated with increased activity of type I iodothyronine 5′-deiodinase in mouse liver

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

Natural Sciences, Virulence Factor, Cpg Motifs +4

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations · Full text

Innate Immune System, Bacteriology, Immunology +18

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

Yukio Sato, Mark Roman, Helen Tighe et al. · Science · 1996 · 1.1K citations

Immunogenetics, Autoimmune Disease, Allergy +14

γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

Maria Gaczyńska, Kenneth L. Rock, Alfred L. Goldberg · Nature · 1993 · 571 citations

Mhc Genes, Protein Function, Protein Expression +8

Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma.

Joel N. Kline, Thomas J. Waldschmidt, Thomas R. Businga et al. · PubMed · 1998 · 550 citations

Inflammation, Asthma, Molecular Immunology +15