CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XXIII. THE EFFECTS OF FEEDING POSSIBLE BLOOD SUBSTITUTES ON SERUM PROTEIN REGENERATION AND WEIGHT RECOVERY IN THE HYPOPROTEINEMIC RAT 1

Paul R. Cannon, Eleanor M. Humphreys, Robert W. Wissler, L. E. Frazier

Journal of Clinical Investigation · 1944 · 37 citations · 1 references

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Abstract

Because of disadvantages connected with the use of the hypoproteinemic dog for the evalua- tion of the biological potencies of small quantities of dietary proteins, we have utilized the hypoproteinemic rat; the present report describes ex- periments in which proteins of possible value as blood substitutes were fed to protein-depleted rats in order to ascertain their abilities to pro- mote serum protein regeneration and weight recovery.

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