INSULIN IN UNIVERSITY OF WISCONSIN SOLUTION EXACERBATES THE ISCHEMIC INJURY AND DECREASES THE GRAFT SURVIVAL RATE IN RAT LIVER TRANSPLANTATION

Abstract

Insulin in UW solution may exacerbate graft ischemic injury and decrease the graft survival rate in rat liver transplantation. Insulin, in the absence of glucose in UW solution, may exhaust the metabolic activity of the liver graft. It is harmful rather than helpful for isolated rat liver grafts preserved in UW solution.