Mitochondrial alterations in dorsal root ganglion cells in sporadic amyotrophic lateral sclerosis

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

Philip C. Wong, Carlos A. Pardo, David Borchelt et al. · Neuron · 1995 · 1.4K citations

Life Sciences, Neurology, Neuroscience +17

Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1

Jiming Kong, Zuoshang Xu · Journal of Neuroscience · 1998 · 716 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Superoxide Dismutase Activity, Oxidative Damage, and Mitochondrial Energy Metabolism in Familial and Sporadic Amyotrophic Lateral Sclerosis

Allen C. Bowling, Jörg B. Schulz, Robert H. Brown et al. · Journal of Neurochemistry · 1993 · 632 citations

Life Sciences, Neurology, Neuroscience +17

The central nervous system in motor neurone disease

Betty Brownell, D. R. Oppenheimer, J. T. Hughes · Journal of Neurology Neurosurgery & Psychiatry · 1970 · 480 citations · Full text

Medicine, Neurology, Pathology +16

Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS)

Mauro C. Dal Canto, Mark E. Gurney · Brain Research · 1995 · 430 citations

Life Sciences, Neurology, Neuroscience +17