Bone cell mechanosensation of fluid flow stimulation: a fluid–structure interaction model characterising the role integrin attachments and primary cilia

Targeted Ablation of Osteocytes Induces Osteoporosis with Defective Mechanotransduction

Sawako Tatsumi, Kiyo‐aki Ishii, Norio Amizuka et al. · Cell Metabolism · 2007 · 836 citations · Full text

Medicine, Orthopedic Surgery, Bone Metabolism +12

Sensitivity of osteocytes to biomechanical stress in vitro

Jenneke Klein‐Nulend, Arie van der Plas, Cornelis M. Semeins et al. · The FASEB Journal · 1995 · 779 citations

Medicine, Physiology, Biomechanics +16

Viscoelastic Properties of the Cell Nucleus

Farshid Guilak, John Tedrow, Rainer Burgkart · Biochemical and Biophysical Research Communications · 2000 · 595 citations

Natural Sciences, Biophysics, Cell Biology +14

Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain

Ichiro Owan, David B. Burr, Charles H. Turner et al. · American Journal of Physiology-Cell Physiology · 1997 · 467 citations

Natural Sciences, Bioengineering, Biophysics +17

Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism

Amanda Malone, Charles T. Anderson, Padmaja Tummala et al. · Proceedings of the National Academy of Sciences · 2007 · 465 citations · Full text

Medicine, Cell Biology, Physiology +17