Targeted Ablation of Osteocytes Induces Osteoporosis with Defective Mechanotransduction

The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation

Kazuhisa Nakashima, Xin Zhou, Gary R. Kunkel et al. · Cell · 2002 · 3.6K citations · Full text

Medicine, Genetics, Molecular Genetics +13

Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

Takashi Shimada, Makoto Kakitani, Y. Yamazaki et al. · Journal of Clinical Investigation · 2004 · 1.4K citations · Full text

Medicine, Endocrinology, Nephrology +17

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

Hiroshi Takayanagi, Kouetsu Ogasawara, Shigeaki Hida et al. · Nature · 2000 · 1.4K citations

Medicine, Cell Biology, Immunology +12

Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling

Xiaofeng Li, Heeseog Kang, Wenzhong Liu et al. · Journal of Biological Chemistry · 2005 · 1.4K citations · Full text

Medicine, Developmental Biology, Molecular Biology +17

Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

Takashi Shimada, Makoto Kakitani, Y. Yamazaki et al. · Journal of Clinical Investigation · 2004 · 1.3K citations · Full text

Medicine, Endocrinology, Nephrology +17