Concepedia

Bone Mechanotransduction

Bone mechanotransduction is the biological process by which bone cells detect mechanical stimuli and convert them into biochemical signals that regulate cellular responses, distinguishing it from other mechanotransductive phenomena by its specificity to skeletal tissue and its role in maintaining bone homeostasis and adaptation.

158

Publications

15.4K

Citations

588

Authors

262

Institutions

Publications per year

2017–2026

38

Parents

Publications

158

Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/Sclerostin

Alexander G. Robling, Paul Niziolek, Lee Ann Baldridge et al. · Journal of Biological Chemistry · 2007 · 1.3K citations · Full text

, , +17

Mechanotransduction in bone—role of the lacunocanalicular network

Elisabeth H. Burger, Jenneke Klein‐Nulend · The FASEB Journal · 1999 · 890 citations

, , +17

Targeted Ablation of Osteocytes Induces Osteoporosis with Defective Mechanotransduction

Sawako Tatsumi, Kiyo‐aki Ishii, Norio Amizuka et al. · Cell Metabolism · 2007 · 836 citations · Full text

, , +12

Low mechanical signals strengthen long bones

Clinton T. Rubin, A. Simon Turner, Steven D. Bain et al. · Nature · 2001 · 717 citations

, , +13

The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents.

Harold M. Frost · PubMed · 1987 · 618 citations

, , +16

1–5 of 158

Authors

588

  1. AG
    Alexander G. Robling

    Indiana University – Purdue University Indianapolis, United States

    11 publications · 2.1K citations

    11

    h-index

  2. CH
    Charles H. Turner

    Indiana University – Purdue University Indianapolis, United States

    8 publications · 2.4K citations

    8

    h-index

  3. CR
    Christopher R. Jacobs

    Stanford University, United States

    8 publications · 2K citations

    8

    h-index

  4. JK
    Jenneke Klein‐Nulend

    Academic Center for Dentistry Amsterdam, Netherlands

    6 publications · 1.4K citations

    6

    h-index

  5. HJ
    Henry J. Donahue

    Pennsylvania State University, United States

    6 publications · 1.1K citations

    6

    h-index

1–5 of 588

Institutions

262

  1. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    14 h-index

    57 publications

    11.2K citations

  2. Indiana University School of Medicine

    Indianapolis, United States

    12 h-index

    41 publications

    9K citations

  3. Stanford University

    Stanford, United States

    7 h-index

    21 publications

    6K citations

  4. Academic Center for Dentistry Amsterdam

    Amsterdam, The Netherlands

    6 h-index

    19 publications

    3.4K citations

  5. Pennsylvania State University

    State College, United States

    6 h-index

    21 publications

    3.3K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    11 publications

    469 citations

  7. Trinity College Dublin

    Dublin, Ireland

    5 h-index

    16 publications

    1.1K citations

  8. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    5 h-index

    18 publications

    3.9K citations

1–8 of 262

Venues

  1. Bone

    15 publications · 1.6K citations

    15

    h-index

  2. Biomechanics and Modeling in Mechanobiology

    11 publications · 383 citations

    11

    h-index

  3. PubMed

    Repository · 12 publications · 1.3K citations

    11

    h-index

  4. Journal of Bone and Mineral Research

    JBMR · 7 publications · 585 citations

    7

    h-index

  5. Journal of Biomechanics

    7 publications · 783 citations

    7

    h-index

1–5