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The antianginal agent ranolazine is a weak inhibitor of the respiratory Complex I, but with greater potency in broken or uncoupled than in coupled mitochondria

MedicinePhysiologyMechanism Of ActionAntianginal Agent RanolazinePharmacotherapyRespiratory ComplexPharmacologyCoupled MitochondriaInhibitory ActivityDrug DiscoveryOxidative Stress