Transcriptional Profile of Aging in C. elegans

Cluster analysis and display of genome-wide expression patterns

Michael B. Eisen, Paul T. Spellman, Patrick O. Brown et al. · Proceedings of the National Academy of Sciences · 1998 · 16.4K citations

Life Sciences, Bioinformatics, Genetics +17

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

Heidi A. Tissenbaum, Leonard Guarente · Nature · 2001 · 1.9K citations

Education, Genetics, Molecular Genetics +10

Extrachromosomal rDNA Circles— A Cause of Aging in Yeast

David Sinclair, Leonard Guarente · Cell · 1997 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Gene Expression Profile of Aging and Its Retardation by Caloric Restriction

Cheol‐Koo Lee, Roger G. Klopp, Richard Weindruch et al. · Science · 1999 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +17

Gene-expression profile of the ageing brain in mice

Cheol‐Koo Lee, Richard Weindruch, Tomas A. Prolla · Nature Genetics · 2000 · 1.1K citations

Life Sciences, Neurobiology, Neuroscience +12