Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE

Richard C. Graham, Morris J. Karnovsky · Journal of Histochemistry & Cytochemistry · 1966 · 6.5K citations · Full text

Medicine, Biochemistry, Nephrology +10

PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY

Ian W. McLean, Paul K. Nakane · Journal of Histochemistry & Cytochemistry · 1974 · 3.8K citations

Medicine, Biochemistry, Cell Biology +17

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

Jennifer Lippincott‐Schwartz, Lydia C. Yuan, Juan S. Bonifacino et al. · Cell · 1989 · 1.7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

Jennifer Lippincott-Schwartz, Julie G. Donaldson, Anja Schweizer et al. · Cell · 1990 · 970 citations

Life Sciences, Cell Biology, Molecular Biology +11

Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum.

Toshiyuki Fujiwara, Kazutaka Oda, Sadaki Yokota et al. · Journal of Biological Chemistry · 1988 · 896 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17