Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

Jennifer Lippincott‐Schwartz, Lydia C. Yuan, Juan S. Bonifacino, +1

Cell

Golgi ApparatusSignal TransductionBrefeldin ABiochemistryOrganelle Dynamic +13

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

Jennifer Lippincott-Schwartz, Julie G. Donaldson, Anja Schweizer, +4

Cell

Signal TransductionNatural SciencesMolecular BiologyCytoskeletonMicrotubule-dependent Retrograde Transport +8

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

Jennifer Lippincott‐Schwartz, Lydia C. Yuan, Christopher Tipper, +3

Cell

Signal TransductionBrefeldin AOrganelle DynamicCell OrganelleNatural Sciences +13

Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence.

Jeffrey S. Humphrey, Peter J. Peters, Lydia C. Yuan, +1

The Journal of Cell Biology

Immunocytochemical TechniqueMolecular BiologyAntigen ProcessingCellular PhysiologyCytoplasmic Tyrosine-containing Sequence +18

Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins.

Javier Garcia Barriocanal, Juan S. Bonifacino, Lydia C. Yuan, +1

Journal of Biological Chemistry

Golgi SystemMedial GolgiGlycobiologyMolecular BiologyCytoskeleton +18

A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules

Victor W. Hsu, Lydia C. Yuan, Jed G. Nuchtern, +3

Nature

Golgi ApparatusSignal TransductionProtein FoldingNatural SciencesEndocytic Pathway +11

The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.

Herbert Bosshart, Ja’Neil G. Humphrey, E. Deignan, +6

The Journal of Cell Biology

Endosomal/lysosomal SystemMolecular BiologyCytoskeletonCellular PhysiologySteady State +16

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.

David L. Wiest, Lydia C. Yuan, J. Jefferson, +6

The Journal of Experimental Medicine

T-regulatory CellImmunologyImmune RegulationAntigen ProcessingCd4 T Cell Responses +14

Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment.

C Chen, Juan S. Bonifacino, Lydia C. Yuan, +1

The Journal of Cell Biology

Adaptive Immune SystemTcr ChainsT-regulatory CellImmunologyMolecular Biology +15

Two integral membrane proteins located in the cis-middle and trans-part of the Golgi system acquire sialylated N-linked carbohydrates and display different turnovers and sensitivity to cAMP-dependent phosphorylation.

Lydia C. Yuan, Javier Garcia Barriocanal, Juan S. Bonifacino, +1

The Journal of Cell Biology

Protein SecretionGolgi SystemGlycobiologyMolecular BiologyIntegral Membrane Proteins +20