Agonist and antagonist affinities for inhibitory adenosine receptors are reciprocally affected by 5'-guanylylimidodiphosphate or N-ethylmaleimide.

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

Peter J. Munson, David Rodbard · Analytical Biochemistry · 1980 · 8.5K citations

Engineering, Biochemistry, Medicine +9

A highly sensitive adenylate cyclase assay

Yoram Salomon, Constantine Londos, Martin Rodbell · Analytical Biochemistry · 1974 · 4.2K citations

Cellular Enzymology, Biochemistry, Molecular Biological Method +4

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

Martin Rodbell · Nature · 1980 · 1.8K citations

Signal Transduction, Biochemistry, Membrane Transduction +12

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

A. De Léan, Jeffrey M. Stadel, Robert J. Lefkowitz · Journal of Biological Chemistry · 1980 · 1.6K citations · Full text

Agonist-specific Binding Properties, Experimental Pharmacology, Ternary Complex Hrx +17