Concepedia

von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase

Shan Hua Li, Yang‐Sook Chun, Ji‐Hong Lim, Eric Huang, Jong‐Wan Park

The International Journal of Biochemistry & Cell Biology · 2011 · 11 citations · 27 references

DOI

Concepts

References

27

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

, , +17

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang et al. · Nature · 1999 · 5.2K citations

, , +14

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science · 2001 · 4.7K citations · Full text

, , +16

Purification and Characterization of Hypoxia-inducible Factor 1

Guang L. Wang, Gregg L. Semenza · Journal of Biological Chemistry · 1995 · 2.1K citations · Full text

, , +14

Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein

Michael Ohh, Cheol Won Park, Mircea Ivan et al. · Nature Cell Biology · 2000 · 1.6K citations

, , +12