Tripeptide inhibitors of dengue and West Nile virus NS2B–NS3 protease

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus

P. Erbel, Nikolaus Schiering, A. D’Arcy et al. · Nature Structural & Molecular Biology · 2006 · 575 citations

Life Sciences, Infectious Diseases, Molecular Biology +16

Purified NS2B/NS3 Serine Protease of Dengue Virus Type 2 Exhibits Cofactor NS2B Dependence for Cleavage of Substrates with Dibasic Amino Acids in Vitro

Rohana Yusof, Stephen Clum, Mary G. Wetzel et al. · Journal of Biological Chemistry · 2000 · 297 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

A Rigorous Test for SPARC's Chemical Reactivity Models: Estimation of More Than 4300 Ionization pK_as

S. H. Hilal, Samuel W. Karickhoff, L. A. Carreira · Quantitative Structure-Activity Relationships · 1995 · 285 citations

Natural Sciences, Chemistry, Analytical Chemistry +15

Functional Profiling of Recombinant NS3 Proteases from All Four Serotypes of Dengue Virus Using Tetrapeptide and Octapeptide Substrate Libraries

Jun Li, Siew Pheng Lim, David Beer et al. · Journal of Biological Chemistry · 2005 · 249 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Update on Dengue: Epidemiology, Virus Evolution, Antiviral Drugs, and Vaccine Development

Annelies Wilder‐Smith, Eng Eong Ooi, Subhash G. Vasudevan et al. · Current Infectious Disease Reports · 2010 · 235 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16