Celastrol suppresses obesity process via increasing antioxidant capacity and improving lipid metabolism

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Medicine, Pharmacotherapy, Preventive Medicine +9

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

Marek Bodzioch, Evelyn Orsó, Jochen Klucken et al. · Nature Genetics · 1999 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +9

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

John McNeish, Robert J. Aiello, Deborah J. Guyot et al. · Proceedings of the National Academy of Sciences · 2000 · 541 citations

Life Sciences, Genetics, Molecular Biology +17

Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

Liam R. Brunham · Journal of Clinical Investigation · 2006 · 513 citations · Full text

Life Sciences, Biochemistry, Physiology +12

Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice

Evelyn Orsó, Cyril Broccardo, Wolfgang E. Kaminski et al. · Nature Genetics · 2000 · 478 citations

Life Sciences, Cell Biology, Molecular Biology +14