Miniaturizable homogenous time-resolved fluorescence assay for carboxypeptidase B activity

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +16

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Yue‐Ming Li, Min Xu, Ming‐Tain Lai et al. · Nature · 2000 · 869 citations

Life Sciences, Biochemistry, Molecular Biology +14

Presenilin 1 is linked with γ-secretase activity in the detergent solubilized state

Yue‐Ming Li, Ming‐Tain Lai, Min Xu et al. · Proceedings of the National Academy of Sciences · 2000 · 535 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Analysis of Heterogeneous βA4 Peptides in Human Cerebrospinal Fluid and Blood by a Newly Developed Sensitive Western Blot Assay

Nobuo Ida, Tobias Hartmann, Johannes Pantel et al. · Journal of Biological Chemistry · 1996 · 479 citations · Full text

Medicine, Neurology, Neuroscience +17

Plasma and Recombinant Thrombin-activable Fibrinolysis Inhibitor (TAFI) and Activated TAFI Compared with Respect to Glycosylation, Thrombin/Thrombomodulin-dependent Activation, Thermal Stability, and Enzymatic Properties

Michael B. Boffa, Wei Wang, Laszlo Bajzar et al. · Journal of Biological Chemistry · 1998 · 195 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14