Age-Related Alteration of Pancreatic β-cell Function: Increased proinsulin and proinsulin-to-insulin molar ratio in elderly, but not in obese, subjects without glucose intolerance - Concepedia

Concepedia

Publication | Closed Access

Age-Related Alteration of Pancreatic β-cell Function: Increased proinsulin and proinsulin-to-insulin molar ratio in elderly, but not in obese, subjects without glucose intolerance

77

Citations

0

References

1996

Year

Mitsuru Shimizu, S Kawazu, Shoichi Tomono, Tomohisa Ohno, Toshihiro Utsugi, Nobuo Kato, C. Ishii, Yoshiharu Ito, Kazuya Murata

Abstract

Alteration of pancreatic beta-cell function independent of that seen with NIDDM occurred in relation to aging. This may be a predisposing factor to the development of impaired glucose tolerance or NIDDM in elderly subjects, that is, independent of obesity.