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Gene Targeting Implicates Cdc42 GTPase in GPVI and Non-GPVI Mediated Platelet Filopodia Formation, Secretion and Aggregation

DOIFull Paper Access

61

Citations

39

References

2011

Year

Huzoor Akbar, Xun Shang, Rehana Perveen, Mark Berryman, Kevin Funk, J. F. Johnson, Narendra N. Tandon, Yi Zheng
PLoS ONE

Abstract

Our data demonstrate that Cdc42 is required for platelet filopodia formation, secretion and aggregation and therefore plays a critical role in platelet mediated hemostasis and thrombosis.

References

YearCitations

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