Huzoor Akbar

A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth <i>In Vitro</i> and <i>In Vivo</i>

Yi Liu, Yanyan Cao, Weihe Zhang et al. · Molecular Cancer Therapeutics · 2012 · 544 citations

Chemoprevention Strategy, Cellular Pharmacology, Metabolic Remodeling +21

Rational Design and Applications of a Rac GTPase–Specific Small Molecule Inhibitor

Huzoor Akbar, José A. Cancelas, David A. Williams et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 2006 · 80 citations

Molecular Docking, Molecular Pharmacology, Drug Targeting +10

Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation

Huzoor Akbar, Jianguo Jin Young B. Kim, Kyle M. Funk et al. · Journal of Thrombosis and Haemostasis · 2007 · 73 citations · Full text

Pharmacologic Evidence, Thrombosis, Thrombopoiesis +12

Gene Targeting Implicates Cdc42 GTPase in GPVI and Non-GPVI Mediated Platelet Filopodia Formation, Secretion and Aggregation

Huzoor Akbar, Xun Shang, Rehana Perveen et al. · PLoS ONE · 2011 · 61 citations · Full text

RhoA and Rac1 GTPases Differentially Regulate Agonist-Receptor Mediated Reactive Oxygen Species Generation in Platelets

Huzoor Akbar, Xin Duan, Saima Saleem et al. · PLoS ONE · 2016 · 40 citations · Full text

Lipid Peroxidation, Reactive Oxygen Species, Platelet Aggregation +19