Concepedia

4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors

John Liddle, Paul Bamborough, Michael D. Barker, Sébastien Campos, Rick Cousins, Geoffrey J. Cutler, Heather Hobbs, Duncan S. Holmes, Christos V. Ioannou, Geoff Mellor,

Bioorganic & Medicinal Chemistry Letters · 2009 · 28 citations · 10 references

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References

10

Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

Yinling Hu, Véronique Baud, Mireille Delhase et al. · Science · 1999 · 826 citations

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The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity

Marc Jacobs, Koto Hayakawa, Lora Swenson et al. · Journal of Biological Chemistry · 2005 · 259 citations · Full text

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Recombinant IκB Kinases α and β Are Direct Kinases of IκBα

Jun Li, Gregory W. Peet, Steven S. Pullen et al. · Journal of Biological Chemistry · 1998 · 71 citations · Full text

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A role for IκB kinase 2 in bipolar spindle assembly

Jeffrey T. Irelan, Thomas J. Murphy, Paul DeJesus et al. · Proceedings of the National Academy of Sciences · 2007 · 70 citations · Full text

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New insights into the structure–function relationships of Rho-associated kinase: a thermodynamic and hydrodynamic study of the dimer-to-monomer transition and its kinetic implications

John Doran, Xun Liu, Paul Taslimi et al. · Biochemical Journal · 2004 · 69 citations · Full text

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